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This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.，推荐阅读51吃瓜获取更多信息
'Taking in my grandchildren has left me penniless'
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В ноябре 2025 года Верховный суд России признал ACF террористической организацией по иску Генеральной прокуратуры. Судебный процесс проходил в закрытом режиме.
Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10187-2，这一点在搜狗输入法2026中也有详细论述